Novitas addresses coding new drugs in our JH Local Coverage Article A52018 Approved Drugs and Biologicals; Includes Cancer Chemotherapeutic Agents. Not Otherwise Classified (NOC) codes should only be reported for those drugs that do not have a valid HCPCS code which describes the drug being administered. When appropriate, the NOC code is selected based upon the therapeutic value of the drug (e.g., J8999 Prescription drug, oral, chemotherapeutic, NOS; J3490 Unclassified drugs, etc.). When billing with an NOC code, include on the claim, the narrative description reflective of the agent and the dose administered.